Parameter
| Biomarker | TP53 | Full name | TP53 gene mutation | Molecular Type | Nucleic acid (DNA) |
|---|---|---|---|---|---|
| Molecular Formula | Macromolecule | Molecular Weight | / | Core Functional Dimensions | Diagnosis and prognosis |
| Disease | Thyroid Cancer | Disease Subtypes | / | ||
| Organ | Thyroid | Test Sample / Technology Platform | Organization (NGS, IHC) | ||
| Pathobiological Mechanisms | Inactivation of tumor suppressor genes accelerates malignant transformation of tumors | ||||
| Clinical Availability Status | Clinical validation: 40% 80% ATC, prompt very poor prognosis | ||||
| Notes and Dynamics | Co-mutation with TERT is the typical molecular feature of ATC | ||||