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707

Parameter
Biomarker TERT promoter Full name TERT promoter mutation Molecular Type Nucleic acid (DNA)
Molecular Formula Macromolecule Molecular Weight / Core Functional Dimensions Prognosis and treatment of prediction
Disease Thyroid Cancer Disease Subtypes /
Organ Thyroid Test Sample / Technology Platform Organization/serum cfDNA sequencing (NGS, methylation)
Pathobiological Mechanisms Longer telomeres, promoting tumor immortalized
Clinical Availability Status Clinical validation: 30% 75% ATC detection, a powerful predictor of risk of recurrence
Notes and Dynamics Liquid biopsy can dynamically monitor disease progression

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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