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709

Parameter
Biomarker TERT promoter Full name TERT promoter mutation Molecular Type Nucleic acid (DNA)
Molecular Formula Macromolecule Molecular Weight / Core Functional Dimensions The prognosis and risk stratification
Disease Thyroid Cancer Disease Subtypes /
Organ Thyroid Test Sample / Technology Platform Tissue (NGS, Sanger sequencing)
Pathobiological Mechanisms Enhance tumor proliferation and invasion ability
Clinical Availability Status In clinical validation: 20%-50% PDTC is present, which is an independent poor prognostic factor
Notes and Dynamics With the mutated BRAF/RAS mutations with elevated risk further

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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