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Parameter
Biomarker PCA3 Full name Prostate Cancer Antigen 3 Molecular Type Nucleic acid
Molecular Formula / Molecular Weight / Core Functional Dimensions Diagnose
Disease PCa Disease Subtypes /
Organ Prostate Test Sample / Technology Platform Urine (RT-PCR)
Pathobiological Mechanisms PCA3 is a non-coding RNA with high prostate cancer specificity. Unlike PSA, PCA3 is highly expressed in prostate cancer cells but is undetectable in normal or benign prostatic hyperplasia.
Clinical Availability Status Clinical routine
Notes and Dynamics It provides guidance for patients with previously negative biopsy results but still clinically highly suspected.

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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