Parameter
| Biomarker | Cortisol | Full name | cortisol | Molecular Type | Hormones |
|---|---|---|---|---|---|
| Molecular Formula | C₂₁H₃₀O₅ | Molecular Weight | 362.46 | Core Functional Dimensions | Diagnosis, Monitoring |
| Disease | Adrenocortical Carcinoma | Disease Subtypes | / | ||
| Organ | Adrenal Cortex | Test Sample / Technology Platform | Serum/urine (immunoassay, LC-MS/MS) | ||
| Pathobiological Mechanisms | Excessive secretion by tumor cells triggers Cushing's syndrome and interferes with glucose and lipid metabolism | ||||
| Clinical Availability Status | Clinical routine application: combined with dexamethasone suppression test for diagnosis; It is used to monitor the treatment response, the sensitivity is 85%+, and the interference of stress and drugs should be excluded | ||||
| Notes and Dynamics | Combined with ACTH, it can be used to identify pituitary Cushing's disease, and imaging localization can assist the diagnosis | ||||