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715

Parameter
Biomarker 17-OHP Full name 17-hydroxyprogesterone Molecular Type Hormones
Molecular Formula C₂₁H₃₀O₃ Molecular Weight 330.46 Core Functional Dimensions Diagnosis and typing
Disease Adrenocortical Carcinoma Disease Subtypes /
Organ Adrenal Cortex Test Sample / Technology Platform Serum (Immunoassay)
Pathobiological Mechanisms "Adrenal cortical hormone synthesis intermediate, abnormal tumor-related synthesis pathway leading to elevated levels.
Clinical Availability Status Clinical auxiliary application: it is used to distinguish congenital adrenal hyperplasia from adrenocortical carcinoma, and the increase in cancer patients is more significant
Notes and Dynamics Can be used as a type of cortisol secretion auxiliary diagnostic markers for cancer improve classification accuracy

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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