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716

Parameter
Biomarker Aldosterone Full name Aldosterone Molecular Type Hormones
Molecular Formula C₂₁H₂₈O₅ Molecular Weight 360.44 Core Functional Dimensions Diagnosis, differential diagnosis
Disease Adrenocortical Carcinoma Disease Subtypes /
Organ Adrenal Cortex Test Sample / Technology Platform Serum/plasma (immunoassay)
Pathobiological Mechanisms Tumor abnormal secretion of water and salt metabolism disorders, rare in adrenal cortical carcinoma, adenoma identification
Clinical Availability Status Clinical differential application: it is used for the screening of primary aldosteronism. Cancer patients are often accompanied by low renin and high aldosterone, and adenoma should be excluded in combination with imaging
Notes and Dynamics Abnormal secretion is rare in cancer, and combined with renin detection can improve the specificity of etiological identification

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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