Parameter
| Biomarker | SF1 (NR5A1) | Full name | Steroidogenic factor 1 | Molecular Type | Protein/nucleic acid |
|---|---|---|---|---|---|
| Molecular Formula | Macromolecule | Molecular Weight | / | Core Functional Dimensions | Diagnosis and typing |
| Disease | Adrenocortical Carcinoma | Disease Subtypes | / | ||
| Organ | Adrenal Cortex | Test Sample / Technology Platform | Tissue (IHC, NGS) | ||
| Pathobiological Mechanisms | Transcription factors regulate adrenocortical cell differentiation and hormone synthesis, and their abnormal expression drives tumorigenesis | ||||
| Clinical Availability Status | Clinical auxiliary application: IHC positive identifiable source of adrenal cortex, used to identify other metastatic tumors | ||||
| Notes and Dynamics | In poorly differentiated carcinoma expression rate is high, can be used as the key to the origin of tumor diagnosis markers | ||||