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725

Parameter
Biomarker β-catenin (nuclear) Full name Nuclear β-catenin protein Molecular Type Protein
Molecular Formula Macromolecule Molecular Weight / Core Functional Dimensions Diagnosis, Prognosis
Disease Adrenocortical Carcinoma Disease Subtypes /
Organ Adrenal Cortex Test Sample / Technology Platform Organization (immunohistochemical IHC)
Pathobiological Mechanisms CTNNB1 gene expression product, check and ratify a hint pathways activated, to participate in the development of tumor
Clinical Availability Status Clinical auxiliary application: nuclear positive expression of support adrenal cortical carcinoma diagnosis and negatively related to the degree of tumor differentiation
Notes and Dynamics It can be used as a marker for protein level verification of CTNNB1 mutation and auxiliary molecular typing

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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