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726

Parameter
Biomarker miR-125b Full name microRNA-125b Molecular Type Microrna (miRNA)
Molecular Formula Macromolecule Molecular Weight / Core Functional Dimensions Diagnosis, prognosis,
Disease Adrenocortical Carcinoma Disease Subtypes /
Organ Adrenal Cortex Test Sample / Technology Platform Serum/organization (RT - qPCR, NGS)
Pathobiological Mechanisms Targeting inhibition of tumor suppressor gene expression, and promote the proliferation and metastasis of tumor cells
Clinical Availability Status Study phase: Low expression in adrenocortical carcinoma, diagnostic AUC of 0.82, correlated with overall survival
Notes and Dynamics Secrete body outside miR - 125 - b testing is expected to become a noninvasive diagnostic and monitoring samples

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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