Parameter
| Biomarker | Citrate | Full name | Citrate | Molecular Type | Organic salt |
|---|---|---|---|---|---|
| Molecular Formula | C6H5O7-3 | Molecular Weight | 189.1 g/mol | Core Functional Dimensions | Diagnose |
| Disease | PCa | Disease Subtypes | / | ||
| Organ | Prostate | Test Sample / Technology Platform | urine, semen, prostatic secretions (proton nuclear magnetic resonance spectrum H-NMR) | ||
| Pathobiological Mechanisms | The zinc level in cancer cells decreases, and the TCA cycle is restored, with citrate being utilized for energy production and lipid synthesis. This results in a significant reduction of citrate levels in tumor tissues. | ||||
| Clinical Availability Status | Research verification | ||||
| Notes and Dynamics | The diagnostic efficacy of citrate combined with PSA requires further clinical validation to facilitate its clinical application. | ||||