Parameter
| Biomarker | DNA methylation (GSTP1, RASSF1, etc.) | Full name | DNA methylation (GSTP1, RASSF1, etc.) | Molecular Type | Nucleic acid |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Diagnosis, prognosis |
| Disease | PCa | Disease Subtypes | / | ||
| Organ | Prostate | Test Sample / Technology Platform | Urine, serum, plasma, tissues (MSRE-PCR, qPCR, whole-genome methylation sequencing) | ||
| Pathobiological Mechanisms | The hypermethylation of gene promoter leads to the silencing of tumor suppressor gene, which leads to the loss of antioxidant function, and affects the cell cycle and apoptosis. | ||||
| Clinical Availability Status | Research verification | ||||
| Notes and Dynamics | Large-scale clinical validation is required. GSTP1 demonstrates high potential for clinical translation. | ||||