Parameter
| Biomarker | Aquaporin family (AQP1, AQP3, etc.) | Full name | Aquaporin family (AQP1, AQP3, etc.) | Molecular Type | Protein |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Prognosis treatment guidance |
| Disease | PCa | Disease Subtypes | / | ||
| Organ | Prostate | Test Sample / Technology Platform | Tumor tissue, urine, and prostate cancer cell lines (IHC, real-time PCR, Western blot) | ||
| Pathobiological Mechanisms | The p38MAPK pathway (AQP1), ERK1/2 pathway (AQP3, AQP9), and RalA/PKA/cAMP pathway (AQP3 membrane localization) collectively drive prostate cancer progression, stem cell maintenance, and metastasis by integrating into complex cellular signaling networks. | ||||
| Clinical Availability Status | Research verification | ||||
| Notes and Dynamics | Due to the lack of large-scale, prospective clinical trials for validation, there is currently insufficient evidence to systematically use AQP for risk stratification. | ||||