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385

Parameter
Biomarker AFP Full name Alpha-Fetoprotein Molecular Type Glycoprotein
Molecular Formula / Molecular Weight / Core Functional Dimensions Diagnose, efficacy monitoring
Disease TGCT Disease Subtypes /
Organ Testis Test Sample / Technology Platform Serum (chemiluminescence immunoassay, electrochemiluminescence immunoassay)
Pathobiological Mechanisms The fetal yolk sac and liver are generated, and re-expressed in NSGCT containing yolk sac tumor components.
Clinical Availability Status Routine clinical application (guideline Standard)
Notes and Dynamics It is not elevated in pure spermatogonial cell tumors. The half-life is 5-7 days. The level is related to tumor load, but it can also be elevated by non-tumor factors such as liver disease.

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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