Parameter
| Biomarker | RFPL3S | Full name | Ret Finger Protein-Like 3S | Molecular Type | Nucleic acid DNA methylation (regulating lncRNA) |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Classification, prognosis, and immunotherapy Prediction |
| Disease | TGCT | Disease Subtypes | / | ||
| Organ | Testis | Test Sample / Technology Platform | Tumor tissue (TCGA, validated) | ||
| Pathobiological Mechanisms | High methylation leads to downregulation of its expression as a tumor suppressor; downregulation is associated with poor prognosis and immune therapy response. | ||||
| Clinical Availability Status | Stage of research | ||||
| Notes and Dynamics | The ability to distinguish between seminoma and non-seminoma, and to predict metastasis and response to immunotherapy. | ||||