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394

Parameter
Biomarker MGM Full name Methylated Gene Marker Molecular Type Nucleic acid DNA methylation
Molecular Formula / Molecular Weight / Core Functional Dimensions Prognosis, treatment prediction
Disease TGCT Disease Subtypes /
Organ Testis Test Sample / Technology Platform Tumor tissue (multiple cohort studies)
Pathobiological Mechanisms High methylation is associated with poor prognosis in some studies, which may be related to cisplatin resistance.
Clinical Availability Status Verification phase
Notes and Dynamics The results were inconsistent, with no methylation detected in non-seminoma in the Indian cohort. It is often analyzed in conjunction with CALCA.

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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