Parameter
| Biomarker | Polygenic signature (7 CpG loci) | Full name | DNA methylation signature | Molecular Type | Nucleic acid DNA methylation |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Prognosis， prediction of chemotherapy sensitivity |
| Disease | TGCT | Disease Subtypes | / | ||
| Organ | Testis | Test Sample / Technology Platform | Tumor tissue (TCGA-derived model) | ||
| Pathobiological Mechanisms | CpG sites associated with genes such as PPMID, PANX1, ENDOD1, MAF, and MYH2; reduced sensitivity to bleomycin and etoposide in the high-risk group. | ||||
| Clinical Availability Status | Stage of research | ||||
| Notes and Dynamics | The prognostic column chart based on bioinformatics findings can predict progression-free survival and chemotherapy sensitivity. | ||||