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400

Parameter
Biomarker ctDNA Full name Circulating Tumor DNA Molecular Type Nucleic acid
Molecular Formula / Molecular Weight / Core Functional Dimensions Diagnose, therapeutic Efficacy Monitoring
Disease TGCT Disease Subtypes /
Organ Testis Test Sample / Technology Platform Plasma (PCR, NGS)
Pathobiological Mechanisms Tumor cell apoptosis/necrosis release, reflecting tumor burden.
Clinical Availability Status Stage of research
Notes and Dynamics Sensitivity 88%, specificity 97%; associated with tumor staging; requires prospective validation

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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