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41

Parameter
Biomarker Anti-Sm antibodies Full name Anti-Smith antibodies Molecular Type Proteins (autoantibodies)
Molecular Formula / Molecular Weight / Core Functional Dimensions Diagnosis
Disease Autoimmune Disease (AD) Disease Subtypes /
Organ Spleen, thymus, lymphoid tissue Test Sample / Technology Platform Serum (immunological assay)
Pathobiological Mechanisms Participates in the immunopathological process of SLE.
Clinical Availability Status Clinically established for definitive SLE diagnosis; aligned with guidelines.
Notes and Dynamics High specificity for SLE; part of the core diagnostic panel.

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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