Parameter
| Biomarker | C3 | Full name | Complement 3 | Molecular Type | Proteins (complement) |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Diagnosis and condition assessment |
| Disease | Autoimmune Disease (AD) | Disease Subtypes | / | ||
| Organ | Spleen, thymus, lymphoid tissue | Test Sample / Technology Platform | Serum (complement quantification) | ||
| Pathobiological Mechanisms | Complement levels reflect the degree of immune activation and consumption. | ||||
| Clinical Availability Status | Clinically used (diagnosis/monitoring); 60%-80% of active SLE patients have reduced C3 levels, with a diagnostic coincidence rate of 75% for disease flares | ||||
| Notes and Dynamics | Low levels correlate with disease activity (flares). | ||||