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47

Parameter
Biomarker Anti-TCP1 antibodies Full name Anti-T-complex Protein 1 antibodies Molecular Type Protein (autoantibody)
Molecular Formula / Molecular Weight / Core Functional Dimensions Diagnosis
Disease Autoimmune Disease (AD) Disease Subtypes /
Organ Spleen, thymus, lymphoid tissue Test Sample / Technology Platform Serum (21K protein microarray, blot analysis, enzyme-linked immunosorbent assay)
Pathobiological Mechanisms The specific expression in serum of SLE patients is elevated, showing significant differences compared to healthy controls and other autoimmune diseases.
Clinical Availability Status Study verification: The positive rate in SLE patients was 79%, significantly higher than that in the control group.
Notes and Dynamics High specificity, serving as a potential biomarker for SLE diagnosis.

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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