Parameter
| Biomarker | Sema4A | Full name | Semaphorin 4A | Molecular Type | Proteins (immunomodulatory molecules) |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Semaphorin 4A |
| Disease | Autoimmune Disease (AD) | Disease Subtypes | / | ||
| Organ | Spleen, thymus, lymphoid tissue | Test Sample / Technology Platform | Whole blood, serum (flow cytometry, ELISA)Whole blood, serum (flow cytometry, ELISA) | ||
| Pathobiological Mechanisms | Elevated plasma soluble concentrations and increased membrane binding ratio on CD4+CD11c+ myeloid dendritic cells are positively correlated with disease activity index. | ||||
| Clinical Availability Status | .Research validation: Demonstrates high sensitivity and specificity in the diagnosis of SLE, enabling differentiation between SLE and RA. | ||||
| Notes and Dynamics | Promising to become a novel diagnostic biomarker for SLE with outstanding discriminative value. | ||||