Parameter
| Biomarker | LINC00667, DANCR | Full name | Long Intergenic Non-Protein Coding RNA 00667, Differentiation Antagonizing Non-Protein Coding RNA | Molecular Type | Nucleic acid (lncRNA) |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Diagnosis, disease activity monitoring |
| Disease | Autoimmune Disease (AD) | Disease Subtypes | / | ||
| Organ | Spleen, thymus, lymphoid tissue | Test Sample / Technology Platform | Plasma exosomes (high-throughput sequencing, RT-qPCR) | ||
| Pathobiological Mechanisms | Significant upregulation of exosomes in the plasma of SLE patients | ||||
| Clinical Availability Status | Research validation: The AUC values were 0.815 and 0.759, respectively, indicating that DANCR can distinguish between active and stable SLE. | ||||
| Notes and Dynamics | Novel biomarkers for SLE diagnosis and activity assessment. | ||||