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Parameter
Biomarker MPV Full name Mean Platelet Volume Molecular Type Hematological indicators
Molecular Formula / Molecular Weight / Core Functional Dimensions Assessment of cumulative damage from diseases
Disease Autoimmune Disease (AD) Disease Subtypes /
Organ Spleen, thymus, lymphoid tissue Test Sample / Technology Platform Whole blood (Complete blood count)
Pathobiological Mechanisms Significantly reduced mean corpuscular volume (MCV) in SLE patients, associated with SLICC score and involvement of kidneys, peripheral vasculature, and musculoskeletal system.
Clinical Availability Status Clinical validation: Can serve as a biomarker for cumulative disease damage.
Notes and Dynamics The test is convenient and can reflect the extent of damage associated with involvement of specific organs.

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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