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Parameter
Biomarker H19 Full name H19 Long Non-Coding RNA Molecular Type Nucleic acid (lncRNA)
Molecular Formula / Molecular Weight / Core Functional Dimensions Diagnosis, disease progression-related
Disease Autoimmune Disease (AD) Disease Subtypes /
Organ Spleen, thymus, lymphoid tissue Test Sample / Technology Platform Serum and peripheral blood mononuclear cells (RT-qPCR, luciferase reporter gene assay).
Pathobiological Mechanisms Upregulated in serum and PBMCs, inhibition of PBMC viability by targeting miR-19b promotes apoptosis and inflammatory responses.
Clinical Availability Status Research validation: demonstrates certain clinical diagnostic value and participates in the regulation of pathological mechanisms.
Notes and Dynamics Providing a novel perspective for understanding the inflammatory mechanisms of SLE.

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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