Parameter
| Biomarker | PS-IgG immune complex | Full name | Phosphatidylserine-Immunoglobulin G immune complex | Molecular Type | Protein (immune complex) |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Diagnosis and pathogenesis-related |
| Disease | Autoimmune Disease (AD) | Disease Subtypes | / | ||
| Organ | Spleen, thymus, lymphoid tissue | Test Sample / Technology Platform | Serum and renal biopsy samples (immunofluorescence staining, flow cytometry) | ||
| Pathobiological Mechanisms | LOX-mediated oxidative stress impairs macrophage phagocytic function, leading to deposition in renal tissues of LN patients. | ||||
| Clinical Availability Status | Research validation: It is a strong biomarker for SLE and LN, and can be targeted by inhibitors through related mechanisms. | ||||
| Notes and Dynamics | Possessing both diagnostic value and therapeutic target potential. | ||||