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56

Parameter
Biomarker CD64 Full name Cluster of Differentiation 64 Molecular Type Protein
Molecular Formula / Molecular Weight / Core Functional Dimensions Disease progression monitoring, pathogenesis-related
Disease Autoimmune Disease (AD) Disease Subtypes /
Organ Spleen, thymus, lymphoid tissue Test Sample / Technology Platform Peripheral blood mononuclear cells (flow cytometry)
Pathobiological Mechanisms Increased expression in circulating monocytes, associated with SLEDAI and anti-Sm antibodies, and involved in the regulation of skin inflammation.
Clinical Availability Status Research validation: Observational SLE progression serves as a mechanistic checkpoint in pathogenesis.
Notes and Dynamics Identify potential targets for interventions related to lupus skin inflammation.

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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