Parameter
| Biomarker | CD21⁻CD27⁻ B cell | Full name | Cluster of Differentiation 21-negative Cluster of Differentiation 27-negative B lymphocyte | Molecular Type | Subpopulation of immune cells |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Assessment of disease activity |
| Disease | Autoimmune Disease (AD) | Disease Subtypes | / | ||
| Organ | Spleen, thymus, lymphoid tissue | Test Sample / Technology Platform | Peripheral blood (mass cytometry, flow cytometry) | ||
| Pathobiological Mechanisms | Increased frequency in SLE patients, correlated with disease severity, unaffected by routine serological markers. | ||||
| Clinical Availability Status | Research validation: Can effectively identify patients with active disease. | ||||
| Notes and Dynamics | To provide reliable and readily available indicators for clinical assessment of disease activity. | ||||