Parameter
| Biomarker | sCD14 | Full name | Soluble Cluster of Differentiation 14 | Molecular Type | Protein |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Disease activity level, renal impairment assessment |
| Disease | Autoimmune Disease (AD) | Disease Subtypes | / | ||
| Organ | Spleen, thymus, lymphoid tissue | Test Sample / Technology Platform | Plasma (ELISA, PCR-RFLP) | ||
| Pathobiological Mechanisms | CD14 (C-159T) polymorphism is associated with susceptibility to SLE, with significantly elevated plasma levels in patients. | ||||
| Clinical Availability Status | Research validation: Positively correlated with SLEDAI-2K score and 24-hour proteinuria. | ||||
| Notes and Dynamics | Higher levels in LN patients serve as novel biomarkers for assessing disease activity and renal impairment. | ||||