Parameter
| Biomarker | L-Pyroglutamic acid | Full name | L-Pyroglutamic acid | Molecular Type | Metabolite |
|---|---|---|---|---|---|
| Molecular Formula | C5H7NO3 | Molecular Weight | 129.12 | Core Functional Dimensions | Diagnosis |
| Disease | Autoimmune Disease (AD) | Disease Subtypes | / | ||
| Organ | Spleen, thymus, lymphoid tissue | Test Sample / Technology Platform | Serum (Liquid Chromatography-Tandem Mass Spectrometry) | ||
| Pathobiological Mechanisms | Significantly elevated in the serum of SLE patients, metabolomics analysis can distinguish patients from healthy controls. | ||||
| Clinical Availability Status | Research verification: At the critical value of 61.54 μM, the AUC was 0.955, with a sensitivity of 97.22% and a specificity of 83.33%. | ||||
| Notes and Dynamics | To provide novel diagnostic biomarkers for heterogeneous and atypical SLE cases. | ||||