Parameter
| Biomarker | CXCL13 | Full name | C-X-C Motif Chemokine Ligand 13 | Molecular Type | Protein (chemokine) |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Diagnosis, assessment of disease activity |
| Disease | Autoimmune Disease (AD) | Disease Subtypes | / | ||
| Organ | Spleen, thymus, lymphoid tissue | Test Sample / Technology Platform | Serum（ELISA） | ||
| Pathobiological Mechanisms | Significantly elevated in the serum of SLE patients, associated with SLEDAI, renal involvement, and active LN. | ||||
| Clinical Availability Status | Research validation: At the critical value of 15.27 pg/mL, the sensitivity was 93.5% and the specificity was 95%. | ||||
| Notes and Dynamics | Unaffected by the status of anti-dsDNA IgG ANA, it serves as a reliable indicator for assessing disease activity. | ||||