Parameter
| Biomarker | GNAS | Full name | GNAS gene mutation | Molecular Type | Nucleic acid (DNA) |
|---|---|---|---|---|---|
| Molecular Formula | Macromolecule | Molecular Weight | / | Core Functional Dimensions | Classification, treatment prediction |
| Disease | Pituitary Adenoma | Disease Subtypes | / | ||
| Organ | Pituitary | Test Sample / Technology Platform | Organization (NGS, Sanger sequencing) | ||
| Pathobiological Mechanisms | Encoding the Gsα protein, mutations activate the cAMP pathway | ||||
| Clinical Availability Status | Clinical application: 40% sporadic GHPA mutations, TuBianZhe of somatostatin analogues (SSA) response is better | ||||
| Notes and Dynamics | With AIP mutations mutexes, can guide individualized treatment | ||||