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738

Parameter
Biomarker ACTH Full name Adrenocorticotropic hormone Molecular Type Hormones
Molecular Formula Macromolecule Molecular Weight / Core Functional Dimensions Macromolecule
Disease Pituitary Adenoma Disease Subtypes /
Organ Pituitary Test Sample / Technology Platform Blood serum/rock under sinus (immune analysis, IPSS)
Pathobiological Mechanisms Excessive secretion lead to Cushing disease, causing elevated cortisol
Clinical Availability Status Clinical routine application: cortisol levels and dexamethasone suppression test confirmed; Source rock under sinus blood ACTH gradient detection can locate
Notes and Dynamics Cushing disease and to identify the core of ectopic ACTH syndrome

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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