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744

Parameter
Biomarker CDKN2A Full name Cyclin-dependent kinase inhibitor 2A gene Molecular Type Nucleic acid (DNA)
Molecular Formula Macromolecule Molecular Weight / Core Functional Dimensions Prognosis, risk stratification
Disease Pituitary Adenoma Disease Subtypes /
Organ Pituitary Test Sample / Technology Platform Organization (methylation sequencing, IHC)
Pathobiological Mechanisms Coding, p16 protein methylation result in cell cycle control
Clinical Availability Status Clinical application: 70% NFPA methylation, positively related to the tumor invasive, the recurrence rate
Notes and Dynamics It is a key indicator for screening high-risk NFPA

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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