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478

Parameter
Biomarker TRbeta Full name Thyroid hormone receptor beta gene mutation Molecular Type Nucleic acid (DNA)
Molecular Formula Macromolecule Molecular Weight / Core Functional Dimensions Diagnosis, typing
Disease Pituitary Adenoma Disease Subtypes /
Organ Pituitary Test Sample / Technology Platform Organization (NGS)
Pathobiological Mechanisms Thyroid hormone receptor gene mutations cause degenerative disorders
Clinical Availability Status Study phase: some TSHPA mutations in, can explain the abnormal secretion of the hormone
Notes and Dynamics Providing theoretical basis for targeted therapy

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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