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Parameter
Biomarker NINJ1 Full name Ninjurin 1 Molecular Type Protein
Molecular Formula / Molecular Weight / Core Functional Dimensions Diagnosis and identification of organ involvement
Disease Autoimmune Disease (AD) Disease Subtypes /
Organ Spleen, thymus, lymphoid tissue Test Sample / Technology Platform Serum (laboratory test)
Pathobiological Mechanisms Significantly elevated in the serum of SLE patients, and further elevated in patients with LN and thrombocytopenia.
Clinical Availability Status Research validation: AUC=0.83, positively correlated with proteinuria, CRP, and NLR.
Notes and Dynamics Assist in identifying renal and hematologic system involvement, facilitating disease stratification.

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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