Parameter
| Biomarker | lncRNA SNHG1 | Full name | Small Nucleolar RNA Host Gene 1 | Molecular Type | Nucleic acid (lnc RNA) |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Diagnosis, pathogenesis-related |
| Disease | Autoimmune Disease (AD) | Disease Subtypes | / | ||
| Organ | Spleen, thymus, lymphoid tissue | Test Sample / Technology Platform | Serum, peripheral blood mononuclear cells (RT-qPCR). | ||
| Pathobiological Mechanisms | Upregulated expression in serum, positively correlated with SLEDAI score and inflammatory markers, regulating PBMC apoptosis. | ||||
| Clinical Availability Status | Research validation: Possesses auxiliary diagnostic potential, and downregulation can inhibit PBMC apoptosis. | ||||
| Notes and Dynamics | Participate in the regulation of SLE inflammation and apoptosis. | ||||