Parameter
| Biomarker | RSAD2 | Full name | Radical S-Adenosyl Methionine Domain Containing 2 | Molecular Type | Protein (iron metabolism-related gene) |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Diagnosis, pathogenesis-related |
| Disease | Autoimmune Disease (AD) | Disease Subtypes | / | ||
| Organ | Spleen, thymus, lymphoid tissue | Test Sample / Technology Platform | Peripheral blood mononuclear cells (bioinformatics analysis, qPCR, Western blot). | ||
| Pathobiological Mechanisms | RSAD2 demonstrated the highest clinical validity (AUC=0.927) and was positively correlated with activated dendritic cells. | ||||
| Clinical Availability Status | Research Verification: RSAD2 knockdown inhibits DC activation and inflammatory mediator expression. | ||||
| Notes and Dynamics | Elucidating the association between immune dysregulation and iron metabolism abnormalities, RSAD2 serves as a potential therapeutic target. | ||||