Parameter
| Biomarker | hsa_circ_0044235, hsa_circ_0001947 | Full name | Homo sapiens Circular RNA 0044235, Homo sapiens Circular RNA 0001947 | Molecular Type | Nucleic acid (circ RNA) |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Diagnosis, prognosis |
| Disease | Autoimmune Disease (AD) | Disease Subtypes | / | ||
| Organ | Spleen, thymus, lymphoid tissue | Test Sample / Technology Platform | Plasma (quantitative reverse transcription PCR) | ||
| Pathobiological Mechanisms | Significantly reduced expression in plasma, serving as an independent risk factor, with significant diagnostic value in combined testing. | ||||
| Clinical Availability Status | Research validation: Differentiates newly diagnosed SLE from healthy controls and RA patients, with correlation to platelet parameters and treatment-related factors. | ||||
| Notes and Dynamics | Non-invasive biomarker, applicable for early diagnosis in newly diagnosed patients. | ||||