Parameter
| Biomarker | DDX5 | Full name | DEAD-Box Helicase 5 | Molecular Type | Protein |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Diagnosis, differential diagnosis |
| Disease | Autoimmune Disease (AD) | Disease Subtypes | / | ||
| Organ | Spleen, thymus, lymphoid tissue | Test Sample / Technology Platform | Serum (ELISA) | ||
| Pathobiological Mechanisms | Significantly elevated serum levels, associated with SLE activity, demonstrate higher diagnostic value when combined with anti-dsDNA and anti-Sm antibodies. | ||||
| Clinical Availability Status | Research validation: AUC=0.976 (combined detection), CBFCM demonstrates superior performance to ELISA. | ||||
| Notes and Dynamics | To provide novel serological markers for the differential diagnosis of SLE and RA. | ||||