Parameter
| Biomarker | sST2 | Full name | Soluble Suppression of Tumorigenicity 2 | Molecular Type | Protein |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Diagnosis, assessment of disease activity |
| Disease | Autoimmune Disease (AD) | Disease Subtypes | / | ||
| Organ | Spleen, thymus, lymphoid tissue | Test Sample / Technology Platform | Serum (laboratory test) | ||
| Pathobiological Mechanisms | Serum levels were significantly elevated, particularly in patients with moderate to severe active disease, and decreased after treatment. | ||||
| Clinical Availability Status | Research validation: The area under the curve (AUC) for distinguishing active disease was 0.959, and for moderate/severe activity was 0.962, demonstrating high sensitivity and specificity. | ||||
| Notes and Dynamics | Associated with multiple clinical and laboratory indicators, it serves as a potential biomarker for pSLE. | ||||