Parameter
| Biomarker | IGHG3 | Full name | Immunoglobulin Heavy Chain Gamma 3 (immunoglobulin fragment) | Molecular Type | Protein (immunoglobulin fragment) |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Diagnosis, disease activity, and renal injury assessment |
| Disease | Autoimmune Disease (AD) | Disease Subtypes | / | ||
| Organ | Spleen, thymus, lymphoid tissue | Test Sample / Technology Platform | Saliva, serum, urine (quantitative laboratory testing) | ||
| Pathobiological Mechanisms | The levels in saliva, serum, and urine were significantly elevated, with urinary IGHG3 showing a positive correlation with SLEDAI and renal involvement. | ||||
| Clinical Availability Status | Research Verification: Urinary IGHG3 levels are significantly higher in nephritis patients compared to non-nephritis patients, and multi-liquid testing can provide complementary results. | ||||
| Notes and Dynamics | Providing multidimensional and non-invasive monitoring indicators for SLE, with outstanding value in renal injury assessment. | ||||