Parameter
| Biomarker | CLEC4E | Full name | C-Type Lectin Domain Family 4 Member E | Molecular Type | Protein |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Diagnosis, disease activity/prognosis assessment |
| Disease | Autoimmune Disease (AD) | Disease Subtypes | / | ||
| Organ | Spleen, thymus, lymphoid tissue | Test Sample / Technology Platform | Peripheral blood (RT-qPCR) | ||
| Pathobiological Mechanisms | High expression in peripheral blood, associated with immune markers, serves as an independent predictor of disease activity. | ||||
| Clinical Availability Status | Research validation: AUC=0.7744 (diagnosis), 0.6360 (activity differentiation), with a combined AUC of 0.9407 when combined with other markers. | ||||
| Notes and Dynamics | High expression is associated with poor prognosis, and combined detection enhances diagnostic and prognostic value. | ||||