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Parameter
Biomarker miR-342-3p Full name microRNA-342-3p Molecular Type Nucleic acid (microRNA)
Molecular Formula / Molecular Weight / Core Functional Dimensions Diagnosis and prognosis assessment
Disease Autoimmune Disease (AD) Disease Subtypes /
Organ Spleen, thymus, lymphoid tissue Test Sample / Technology Platform Serum (qRT-PCR)
Pathobiological Mechanisms Significantly reduced expression in serum, negatively correlated with SLEDAI, with low expression indicating poor prognosis.
Clinical Availability Status Research validation: ROC curve distinguishes SLE from healthy controls, while log rank analysis indicates poor prognosis in the low-expression group.
Notes and Dynamics Possesses both diagnostic and prognostic value, providing a basis for risk stratification.

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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