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756

Parameter
Biomarker INS Full name Insulin Molecular Type hormone
Molecular Formula C₂₅₇H₃₈₃N₆₅O₇₇S₆ Molecular Weight 5807.6 Core Functional Dimensions Diagnosis, Monitoring
Disease Pancreatic Neuroendocrine Tumors Disease Subtypes /
Organ Pancreas Test Sample / Technology Platform Serum (immunoassay)
Pathobiological Mechanisms Excessive secretion of β-cell-derived tumors leads to hypoglycemia syndrome
Clinical Availability Status The diagnostic sensitivity was 52-94% in combination with Whipple's triad (hypoglycemia, blood glucose ≤40mg/dL, remission with sugar supplementation)
Notes and Dynamics It is a core diagnostic marker for insulinoma, and monitoring its level after operation can evaluate the efficacy of surgery

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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