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757

Parameter
Biomarker GAS Full name Gastrin Molecular Type Hormones
Molecular Formula Macromolecule Molecular Weight / Core Functional Dimensions Diagnosis, Monitoring
Disease Pancreatic Neuroendocrine Tumors Disease Subtypes /
Organ Pancreas Test Sample / Technology Platform Serum (immunoassay)
Pathobiological Mechanisms G cell-derived tumor secretion, causing Zolie-Ellison syndrome (high gastric acid, peptic ulcer)
Clinical Availability Status High clinical specificity: serum level ≥300pg/mL suggests gastrinoma, and patients with MEN1 syndrome should be preferentially screened
Notes and Dynamics The diagnostic sensitivity can be improved when combined with CgA

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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