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Parameter
Biomarker NSE Full name Neuron-specific enolase Molecular Type Protein
Molecular Formula Macromolecule Molecular Weight / Core Functional Dimensions Prognosis, Monitoring
Disease Pancreatic Neuroendocrine Tumors Disease Subtypes /
Organ Pancreas Test Sample / Technology Platform Serum (Immunoassay)
Pathobiological Mechanisms Neuroendocrine cell-specific enolase, reflecting tumor burden and differentiation degree
Clinical Availability Status Clinical assistance: 30-50% PanNENs were elevated, and those with G3 and metastasis had higher levels. Combined with CgA, the disease progression was monitored
Notes and Dynamics The specificity of CgA is lower than that of CgA, and interferons such as neurogenic tumors should be excluded

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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