Parameter
| Biomarker | TNF alpha | Full name | Tumor necrosis factor alpha | Molecular Type | Proteins |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | 17 kDa | Core Functional Dimensions | Susceptibility, prognosis |
| Disease | hypertension | Disease Subtypes | / | ||
| Organ | Macrophages, monocytes, T cells | Test Sample / Technology Platform | Serum/plasma (ELISA, chemiluminescence) | ||
| Pathobiological Mechanisms | It activates inflammatory pathways in vascular endothelial cells, increases vascular permeability, induces oxidative stress and vasoconstriction | ||||
| Clinical Availability Status | Research validation/clinical exploration: It is used to evaluate the degree of inflammation in hypertension, but has not been routinely used in clinical practice | ||||
| Notes and Dynamics | Related to vascular stiffness in patients with hypertension, biological agents targeting TNF-α have shown antihypertensive potential in experimental models | ||||