Parameter
| Biomarker | CCL2/MCP-1 | Full name | Monocyte chemoattractant protein-1 | Molecular Type | Protein |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | 13 kDa | Core Functional Dimensions | Susceptibility, monitoring |
| Disease | hypertension | Disease Subtypes | / | ||
| Organ | Vascular endothelial cells, macrophages, smooth muscle cells | Test Sample / Technology Platform | Serum/plasma (ELISA, multiplex immunoassays) | ||
| Pathobiological Mechanisms | Chemokines monocyte infiltration blood vessels, promote macrophage activation and foam cell formation, accelerate the blood vessel damage | ||||
| Clinical Availability Status | Validation: in high blood pressure is widely used in the research of vascular inflammation and progress is expected to be used to monitor the blood vessel damage | ||||
| Notes and Dynamics | CCR2 antagonists can reduce hypertension model of vascular inflammation, related drugs in preclinical research and development stage | ||||