Parameter
| Biomarker | ICAM-1 | Full name | Intercellular adhesion molecule 1 | Molecular Type | Protein |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | 80-110 kDa | Core Functional Dimensions | Susceptibility, monitoring |
| Disease | hypertension | Disease Subtypes | / | ||
| Organ | Vascular endothelial cells, epithelial cells | Test Sample / Technology Platform | Serum/plasma (ELISA, immunoturbidimetry) | ||
| Pathobiological Mechanisms | It can enhance the adhesion and migration of white blood cells to endothelial cells, activate inflammatory signaling pathways, and aggravate vascular injury | ||||
| Clinical Availability Status | Clinical exploration/research validation: used to evaluate the inflammatory state of blood vessels in hypertension, some used in clinical research | ||||
| Notes and Dynamics | ICAM-1 neutralizing antibody can reduce the blood pressure of hypertension model, provide new ideas for targeted therapy | ||||